Publishing company Wiley (NYSE: WLY) announced on Tuesday that the 23rd Annual Wiley Prize in Biomedical Sciences will be awarded to Iva Greenwald and Spyros Artavanis-Tsakonas for their groundbreaking research on Notch signaling. Their discovery of the genes and biochemical mechanisms governing Notch signaling has been pivotal in understanding cell fate decisions in metazoans, with significant implications for human health and disease.

Iva Greenwald, Da Costa Professor of Biology at Columbia University, and Spyros Artavanis-Tsakonas, Professor Emeritus of Cell Biology at Harvard Medical School, are being honoured for their work on this critical signaling pathway. Notch signaling allows cells to determine the fate of neighbouring cells, a process central to various biological functions.

Dr Titia de Lange, Chair of the Wiley Prize jury, highlighted the distinctive nature of the Notch pathway and its vital role in human biology.

Deborah Wiley, Chair of the Wiley Foundation, emphasized the recipients' contributions in laying the foundation for understanding both normal and disease-related development, opening avenues for new medical treatments.

The Wiley Prize will be presented during a lecture at The Rockefeller University on 18 April 2025, with a recording available on the Wiley Foundation website. Since its inception in 2002, the Wiley Prize has recognised pioneering biomedical research, with numerous recipients later awarded Nobel Prizes in Physiology, Medicine and Chemistry.

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